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        Skip Navigation LinksPharma/United States - English/Grace Silica Excipients Carriers Drug Delivery Mesoporous - SYLOID® - SILSOL®



        Uniquely Functional Excipients

        Imagine what you could do working with a partner who can engineer products to your exact specifications and minimize the number of excipients and complexity of your formulation, while expediting manufacturing and improving the efficacy and stability of your API's final dosage form. 

        Our SYLOID? mesoporous silica's particles have a unique combination of properties.

        We can fine-tune parameters such as pore volume, pore diameter, pore size distribution, and internal surface area to modify the functionality and meet your exact requirements.

        • SYLOID? AL-1FP/63FP silicas control trace amounts of moisture and moisture transfer from the surrounding environment which can degrade APIs or cause reactions that negatively impact drugs or decrease shelf life.
        • SYLOID? G silica for glidant applications is specifically designed as a cost effective glidant in pharmaceutical formulations.
        • SYLOID? 244 FP is a real multi-purpose excipient that can be used in all oral dosage drug forms and for tablet coating. It offers moisture protection, anti-tacking properties, and acts as a glidant and suspension aid.

        SYLOID? XDP silica carrier is an optimized mesoporous material engineered for transforming liquids to free-flowing solids, particularly oily actives and lipid-based systems.

        SYLOID? FP Mesoporous 
        Silic a Excipients  
        SYLOID? FP mesoporous silicas are the ideal choice for many pharmaceutical formulations due to its unique morphology to help improve the handling, adsorption, and the dissolution of many pharmaceuticals.
        • Effective desiccant to increase the stability of moisture-sensitive APIs
        • Efficient conditioner for powder formulations used in suspension s
        • Capillary wetting agent for better release and disintegration
        • Contribution to the controlled release of active pharmaceutical ingredients (API)
        • Low dusting and easy to handle
        SYLOID? XDP  Silica  
        Pharmaceutical Excipients
        SYLOID? XDP silica carrier is an optimized mosoporous material engineered for transforming liquids to free-flowing solids, particularly oily actives, and lipid-based systems.
        • Solid carrier for lipid-based drug delivery systems
        • Transform liquids to easy to handle solids
        • Improve bioavailability of oily actives
        • Increase API loading in solid dosage forms
        • Release API's quickly and completely from solid dosage forms
        • Create liquisolid formulations
        SILSOL?  Silica for Drug Delivery SystemsSILSOL? silica was engineered to bring together advanced silica technologies with challenging active pharmaceutical ingredients to help more effectively formulate large class of poorly soluble but otherwise promising compounds.
        • Enhanced bioavailability - through delivery of the amorphous form of drugs
        • Stability - amorphous solid dispersions prevent crystallization/re-crystallization
        • Pharmacopeia acceptance - GMP manufactured silica
        • Scalability -  Grams to tons quantities
        • FDA Compliance – Materials listed in FDA inactive ingredient database

        Technical Papers

        SYLOID? FP SilicaSYLOID? XDP Silica


        SILSOL? Silica-based Drug Delivery


        Grace's silica excipients are made according to Good Manufacturing Practices (cGMP) guidelines and our compendial materials meet the requirements published in the latest edition of the United States Pharmacopoeia-National Formulary (USP-NF) for Silicon Dioxide, European Pharmacopeia, and JPE monographs. SYLOID? silicas are also listed on the FDA inactive ingredient database. Additionally, we are proud to be foremost in Industry Leading Quality Standards (Excipact? -GMP).